Tottenham Hotspur will take the decision on defender Kieran Trippier, who could still play after an ankle problem.
Danny Rose (knee), Erik Lamela (hip) and Georges-Kevin Nkoudou remain unavailable.
Tiemoue Bakayoko could be included in the Chelsea squad for the first time after recovering from a knee injury.
Pedro (ankle) is still doubtful despite returning to the training and Eden Hazard (also ankle) is not yet fully fit, though is believed to be close to a return. Gary Cahill and Cesc Fabregas are suspended.
Did you know?
This will be the first Premier League match played at Wembley Stadium and it will be the 58th different stadium to host a match in the PL history.
Chelsea have lost only two of their last 17 matches in all competitions against Tottenham Hotspur (W8 D7 L2).
But Spurs haven’t lost a Premier League London derby at home under Mauricio Pochettino (W9 D4 L0).
Chelsea must be desperately looking to avoid becoming the first reigning champions to lose their opening two matches of the following PL season.
What the managers say:
Mauricio Pochettino: “It is tough to play against Chelsea, but we are excited after the result against Newcastle, so we are confident and now we must apply everything and try to win.”
Antonio Conte: “We must be focused on the pitch, on the game and try to do our best against Tottenham and not find excuses, but only focus on the game.”
— Tottenham Hotspur (@SpursOfficial) August 20, 2017
— Chelsea FC (@ChelseaFC) August 20, 2017